招生院所：药学院

招生类型：学术学位(硕)

招生专业：药剂学

研究方向名称：多肽序列设计、超分子组装及光化学功能构筑

电子信箱：nanxie@ccmu.edu.cn

个人简介

承担《有机化学》、《有机化学实验》、《基础化学实验》等课程教学工作。围绕多肽分子设计、超分子组装及其光化学构筑开展研究，建立了序列驱动的水凝胶直接构建体系，致力于实现从头设计多肽编码序列到功能水凝胶材料快速制备及生物医学特色应用。主持国家自然科学基金、北京市自然科学基金、北京市教委科技计划项目及首都医科大学自然科学基金等多项课题。在 Nano Research 、 Biomacromolecules 、 ACS Applied Nano Materials 等期刊发表学术论文30余篇。

教育经历

2002.09-2007.07，中科院理化所，博士

1998.09-2002.07，河南师范大学，学士

工作经历

2015.01-至今，首都医科大学，副教授

2009.06-2014.12，首都医科大学，讲师

2007.08-2009.05，美国佐治亚州立大学，博士后

重要学术论文：

1. Xiang Shu, Zhaoyang Wang, Ying Wen, Yuexin Shi, Xue-Wang Gao, Shumin Yang, Jianqun Shao, Ke Feng, Bin Chen, Nan Xie*, Chen-Ho Tung, Li-Zhu Wu*, Photochemically Fabricated Peptide Hydrogels from De Novo  Design to Application in Antibacterial Therapy and Wound Healing, Nano Res. , 2026, 19(5) , 94908544.

2. Sijie He, Xiang Shu, Zhaoyang Wang, Xue-Wang Gao, Ke Feng, Sumin Yang, Jianqun Shao, Nan Xie*, Photofabrication of Fluorescent Nanospheres from De Novo  Designed Peptides, and Their Enzyme-Responsive Dissociation in Living Cells, Mater. Adv. , 2024, 5(7) , 2888-2897.

3. Jingyi Zhao, Chen Li, Xue-Wang Gao, Ke Feng, Hao Liu, Sijie He, Wenhua Zhao, Shumin Yang, Jianqun Shao, Ling Ye, Bin Chen, Nan Xie*, Chen-Ho Tung, Li-Zhu Wu*, Quick Photofabrication of Functional Nanospheres from De Novo  Designed Peptides for NIR Fluorescence and MR Imaging, Nano Res. , 2023, 16(3) , 4029-4038.

4. Hao Liu, Sijie He, Li-Ya Niu, Xue-Wang Gao, Ke Feng, Shumin Yang, Jianqun Shao, Wenhua Zhao, Nan Xie*, Qing-Zheng Yang, Peptide Photowrapping of Gold-Silica Nanocomposites for Constructing MMP-Responsive Drug Capsules for Chemo-Photothermal Therapy, Chem. Commun. , 2023, 59(34) , 5059-5062.

5. Kun-Xu Teng, Li-Ya Niu, Nan Xie, Qing-Zheng Yang, Supramolecular Photodynamic Agents for Simultaneous Oxidation of NADH and Generation of Superoxide Radical, Nat. Commun. , 2022, 13(1) , 6179.

6. Chen Li, Ke Feng, Nan Xie*, Wenhua Zhao, Ling Ye, Bin Chen, Chen-Ho Tung, Li-Zhu Wu, Mesoporous Silica-Coated Gold Nanorods with Designable Anchor Peptides for Chemo-Photothermal Cancer Therapy, ACS Appl. Nano Mater. , 2020, 3(6) , 5070-5078.

7. Si-Meng Wei, Ke Feng, Chen. Li, Nan Xie, Yang Wang, Xiu-Long Yang, Bin Chen, Chen-Ho Tung, Li-Zhu Wu, ZnCl₂ Enabled Synthesis of Highly Crystalline and Emissive Carbon Dots with Exceptional Capability to Generate O₂^•–, Matter ,2020, 2(2) , 495-506.

8. Nan Xie*, Ke Feng*, Jianqun Shao, Bin Chen, Chen-Ho Tung, Li-Zhu Wu*, Luminescence-tunable Polynorbornenes for Simultaneous Multicolor Imaging in Subcellular Organelles, Biomacromolecules , 2018, 19(7) , 2750-2758.

9. Nan Xie, Ke Feng*, Jianqun Shao, Bin Chen, Chen-Ho Tung, Li-Zhu Wu*, A Simple, Modular Synthesis of Bifunctional Peptide-Polynorbornenes for Apoptosis Induction and Fluorescence Imaging of Cancer Cells, Polym. Chem. , 2018, 9(1) , 77-86.

10. Ke Feng^#, Nan Xie^#,Bin Chen, Chen-Ho Tung,Li-Zhu Wu, Modular Design of Poly(norbornenes) for Organelle-Specific Imaging in Tumor Cells, Biomacromolecules , 2016, 17 (2) , 538-545. (^#equal contribution)

11. Nan Xie, Ke Feng, Bin Chen, Ming Zhao, Li-Ping Zhang, Chen-Ho Tung, Li-Zhu Wu, Shiqi Peng, A Modular Designed Copolymer with Anti-Thrombotic Activity and Imaging Capability, Chem. Commun. , 2014, 50 (67) , 9539-9542.

12. Nan Xie, Ke Feng, Bin Chen, Ming Zhao, Shiqi Peng, Li-Ping Zhang, Chen-Ho Tung, Li-Zhu Wu, Water-soluble copolymeric materials: switchable NIR two-photon fluorescence imaging agents for living cancer cells, J. Mater. Chem. B , 2014, 2 (5) , 502-510.

13. 谢楠，赵静怡，刘昊，何思洁. 一种全肽纳米胶球的光化学合成方法. 中国发明专利，授权专利号：ZL202210008394.X，授权日：2025-03-14。